Babul Ki Duwayen Leti Ja revolves around five sisters among whom Sheetal is the eldest. She is like a mother to her sisters. She takes care of all the responsibilities of her family and her sisters. The five sisters have their own dreams and the serial is about their lives and the struggle they face to fulfil their dreams. Sheetal wants to give all happiness to her sisters and sacrifices her dreams and her love life also for her sister.